Infrastructure

Our lab has state-of-the-art analytical chemistry and synthetic biology facilities for

  • (Bio)synthesis, detection, purification and structural characterization of microbial metabolites and other molecules

  • Growth and genetic manipulation of aerobic and anaerobic biosafety level 1 and 2 microorganisms

  • Enzyme purification, engineering and in vitro biochemical analysis

Chemistry

  • Echo-MS system with a SCIEX Triple Quad 6500+ MS
  • Dionex Ultimate 3000 UHPLC coupled to a Bruker Impact II ESI-Q-TOF MS
  • Thermo Scientific Trace GC coupled to an ISQ single quadrupole MS
  • Automated flash chromatography system with UV-Vis and ELS detection
  • Access to 300, 500 and 600 MHz Bruker NMR spectrometers
  • Semi-preparative, preparative and analytical HPLCs
  • Chemical fume hoods
  • Rotary evaporators
  • Lyophiliser

Biology

  • Fluorescence, luminescence and absorbance microplate readers
  • eProtein Discovery System from Nuclera
  • Sonication and electroporation equipment
  • Real-time and gradient PCR machines
  • New Brunswick Innova shaking incubators
  • NanoDrop spectrophotometer
  • Electrophoresis systems
  • Anaerobic workstation
  • Various centrifuges